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المقالات الاكاديمية والبحثية
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The main objective of this study was to determine the phytochemical composition in the leaves of
Coriandrum sativum, using methanolic extraction and report the main functional components by using
IR technique. The phytochemical compounds in the extract were then screened by GC-MS method.
Seven bioactive phytochemical compounds were identified in the methanolic extract of C. sativum: 1,6-
octadien-3-ol, 3,7-dimethyl, 1,6-octadien-3-ol,3,7-dimethyl, 2-aminobenzoate, bicyclo[2.2.1]heptan-2-
one,1,7,7-trimethyl., geranyl vinyl ether, 9,10-secocholesta-5,7,10(19)-triene-3,24,25-triol., ascorbic acid
2,6-dihexadecanoate and 7aH-cyclopenta[a] cyclopropa[f]cycloundecene. Thirteen bioactive
phytochemical compounds were identified in the methanolic extract of Melia azedarach. In the present
investigation, a variety of compounds have been detected in M. azedarach including trichloromethane,
propanedioic acid, diethyl ester, 2-pyrrolidinyl-methylamine, butanedioic acid, diethyl ester, 2-
piperidimethanamine, butanedioic acid, hydroxyl-, diethyl ester, 2,5-dimethylhexane-2,5-
dihydroperoxide, dithiocarbamate, s-methyl-,n-(2-methyl-3-oxobutyl), triethyl citrate, y-sitosterol, ethyl
9,12,15-octadecatrienoate, hexadecanoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester, and octadecane,
3-ethyl-5-(2-ethylbutyl). It contains chemical constitutions which may be useful for various herbal
formulation as anti-inflammatory, analgesic, antipyretic, cardiac tonic and antiasthamatic. C. sativum is
highly active against Aspergillus terreus 6.01 ± 0.200. Bioactive compounds of C. sativum and M.
azedarach were assayed for in vitro antibacterial activity against Staphylococcus aureus, Proteus
mirabilis, Pseudomonas aerogenosa, Escherichia coli and Klebsiella pneumonia using the diffusion
method in agar. The zone of inhibition was compared with different standard antibiotics. The diameters
of inhibition zones ranged from 5.60 ± 0.320 to 1.96 ± 0.200 mm for all treatments.

  • وصف الــ Tags لهذا الموضوع
  • Anti-bacterial, antifungal activity, Coriandrum sativum, GC-MS analysis, Melia azedarach, phytochemicals.

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